Reversible decatenation of kinetoplast DNA by a DNA topoisomerase from trypanosomatids
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چکیده
منابع مشابه
Reversible decatenation of kinetoplast DNA by a DNA topoisomerase from trypanosomatids.
DNA topoisomerase activity detected in cell extracts of the trypanosomatid Crithidia fasciculata interlocks kinetoplast DNA duplex minicircles into huge catenane forms resembling the natural kinetoplast DNA networks found in trypanosomes. Catenation of duplex DNA circles is reversible and equilibrium is affected by ionic strength, and by spermidine. The reaction requires magnesium, is ATP depen...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1983
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/11.12.4019